Adenosine triphosphate concentration and the synthesis of acetylcholine by brain preparations
作者： Hugh McLennan , K.A.C. Elliott
DOI: 10.1016/0003-9861(52)90380-9
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摘要: Abstract Synthesis of acetylcholine (ACh) by supplemented brain extracts is strongly dependent on the adenosine triphosphate (ATP) concentration below about 2 μmoles/ml. Respiring slices contain 30 μmoles acid-labile phosphate/g. Due to action apyrase, respiring suspensions virtually no ATP. While synthesis ACh and greatly increased a high potassium concentration, this does not occur with suspensions, presumably because limited low ATP which can exist in such suspensions.
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