Myoclonic seizures subside in the fourth decade in juvenile myoclonic epilepsy.

摘要: Objective: Our aim was to assess the long-term follow-up of juvenile myoclonic epilepsy (JME), with an emphasis on course seizures. Methods: We enrolled 48 patients JME (29 F, 19 M; aged 39.9 ± 9.5 years) followed up for a mean 19.6 5.7 years. The remission 5 years and relapses were evaluated all seizure types changes in severity/frequency myoclonia systematically questioned. clinical EEG features, antiepileptic drug (AED) treatment regimen, systemic psychiatric comorbid diseases evaluated. Results: found benign 66.6% whereas 16.7% had pseudo-resistance due problems or lifestyle. true-resistant observed remaining significantly associated disorders presence thyroid diseases. In 54.2% patients, duration 8.4 7.7 years, after average age 32.9 9.6. Of these 6 lower dose AED comparison dosage needed control seizures beginning, stopped treatment. None latter 11 except one relapsed during follow-up. Furthermore, 21 other (43.8%) described substantial alleviation 31.3 severity myoclonia. Conclusion: Although great majority continuing 20 almost either 5-year