Ultra-sonication-assisted silver nanoparticles using Panax ginseng root extract and their anti-cancer and antiviral activities.

摘要: Abstract A simple, inexpensive ultra-sonication method was used to synthesize quasi spherical silver nanoparticles (AgNPs) with an aqueous extract from Panax ginseng roots. This has the advantages of being completely eco-friendly and allows increased reaction rates, uniform dispersal in liquids, effective breaking aggregates. Biomolecules present plant extracts are often reduce metal ions a single-step green synthesis route. The formation AgNPs characterized using UV–visible (UV–vis) spectroscopy, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), energy- dispersive analysis (EDX), Fast Transform (FFT), high-resolution transmission electron microscopy (HR-TEM). (456 nm) confirmed by UV–vis spectroscopy. HR-TEM revealed that most were sizes ranging approximately 5 15 nm. crystalline nature XRD, presence elemental energy-dispersive X -ray analysis. showed dose-dependent cytotoxicity towards HeLa cells vitro (3.88% at 0.005 M, 5.11% 0.01 M, 7.52% 0.015 M, 11.19% 0.02 M, 19.45% 0.025 M) as sulforhodamine B assay. They also shown be virucidal against influenza virus (strain A/PR/8). Hence, facile, eco-friendly, efficient results can act alternative biomaterial for future biomedical applications.