作者: Katharina Wirth , Raphael S. Peter , Christoph H. Saely , Hans Concin , Gabriele Nagel
DOI: 10.1371/JOURNAL.PONE.0127186
关键词:
摘要: Little is known about the associations between long-term weight change and natural history of impaired fasting glucose (IFG) in young adults. We investigated association body mass index (BMI) risk IFG using data 24,930 20- to 40-year-old participants from Vorarlberg Health Monitoring Promotion Program (VHM&PP) cohort. Poisson models were applied estimate 10-year for new development (≥5.6 mmol/L), persistence IFG. Over 10 years, most men (68.2%) women (70.0%) stayed within their initial BMI category. The incident was highest with persisting obesity (37.4% 24.1%) lowest normal (15.7% 9.3%). Men transitioning overweight increased by factor 1.45 (95%-CI: 1.31, 1.62), 1.70 1.50, 1.93), whereas decreased 0.69 0.53, 0.90) 0.94 0.66, 1.33) women. Relative risks 0.58 0.44, respectively. In conclusion, year increase associated an risk, decrease a