Artificial neural network posturography detects the transition of vestibular neuritis to phobic postural vertigo

摘要: Artificial neural networks (ANNW), described in detail by Duda et al. [1], can be efficiently used to master complex data sets applying computational analysis for routine clinical uses, example, classify the risk of falls elderly on basis an balance control during gait [2]. In earlier study we ANNW posturography identify typical postural sway patterns that allow diagnosis various disorders [3]. Body was measured means ten test conditions increasing difficulty. These included standing with eyes open or closed, head extended backward, a slab foam rubber, and tandem stance. Sixteen values were selected from calculated parameters each single condition, such as path, root mean square values, Fourier analysis. This total 160 entered into artificial network (for methods, see [3]). this way standard three-layer, feed-forward uses backpropagation algorithm trained training cases, validated validation its accuracy tested new cases diagnoses. The sensitivity specificity about 0.9 patients vestibular neuritis phobic vertigo. Once designed tested, ANNW-posturography considered black box, which examiner apply predict specific even without preceding examination. Here would like present example two demonstrate relevance method. case 1 method able disclose transition patient acute underwent vertigo within months after disease onset. 2 it confirmed patient’s recovery static despite permanent unilateral loss. Case 1: 70-year-old male presented signs symptoms acute, left-sided failure. A deficit function diagnosed pathological head-impulse revealed presence corrective (catch-up) saccades caloric irrigation showed non-responsiveness left horizontal semicircular canal. Since there no other neurological deficits, he have leftsided neuritis. further supported probability 93% (Fig. 1a). Dizziness imbalance recovered gradually weeks due central compensation, although restitution peripheral function. again ski. Five later, however, complaints subjective unsteadiness, invisible observer. He had attack-like exacerbations fear falling any real falls. now exhibited T. Brandt (&) Institute Clinical Neurosciences Integrated Research Treatment Center Vertigo, Balance Ocular Motor Disorders (IFB), Ludwig Maximilian University, Marchioninistr. 15, 81377 Munich, Germany e-mail: thomas.brandt@med.uni-muenchen.de