Chronic subdural hematomas and seizures: the role of prophylactic anticonvulsive medication.

摘要: BACKGROUND The rates of seizure activity associated with surgical treatment chronic subdural hematoma (CSH) reported in the literature has varied greatly. efficacy prophylactic anticonvulsive medication (ACM) been debated and its use erratic. With improved diagnosis, reduction morbidity impacts greatly on mortality rate, so ACM may be important to patient CSH. METHODS We conducted a retrospective analysis records patients treated surgically for CSH examined prevalence activity, morbidity, effects anticonvulsant medication. RESULTS Ninety-eight (65 = male) were identified mean age 72 years range 4 97 years. Six had preexisting disorder; despite therapeutic serum levels ACM, 3 these 6 experienced seizures without mortality. Seizures occurred 20/98 (20.4%) during hospitalization or follow-up. Of 92 disorder, 42 (46%) received phenytoin levels. One among (2.4%) who comparison 16 50 (32%) did not receive adequate (P < 0.001). 11 deaths within one month discharge new onset 0.005). Age, sex, history trauma, Markwalder scores admission, location hematoma, type surgery unrelated occurrence Following hospital discharge, continued duration 8 months seizures. CONCLUSIONS was found 17 (18.5%) increases Patients demonstrated significant decrease seizures, we therefore recommend prophylaxis hematoma.