First human use of the Hemopump, a catheter-mounted ventricular assist device

摘要: The Hemopump, a catheter-mounted, temporary ventricular assist device, consists of an external electromechanical drive console and disposable, intraarterial axial-flow pump (21F). Power is transmitted percutaneously to the by flexible shaft within catheter. device positioned in left ventricle way femoral artery approach or through ascending aorta. Blood drawn from transvalvular inlet cannula pumped into As December 1988, Hemopump had successfully supported circulation 7 patients (5 men, 2 women) ranging age 44 72 years (mean age, 59 years) suffering cardiogenic shock (cardiac index less than 2.0 L/min/m2). Indications for use included failure be weaned cardiopulmonary bypass 4 patients, acute myocardial infarction 1, severe cardiac allograft rejection donor heart 1. Duration support ranged 26 113 hours (mean, 66 hours). Although 5 demonstrated transient hemolysis, none experienced infection, thrombosis, vascular injury. Hemodynamic variables improved all during device. were alive more 30 days after been discontinued, 3 these discharged hospital. On basis our initial clinical results, which does not require major surgical procedure insertion, provides effective, circulatory with potentially reversible failure.