Spiro-linked pyrrolidine-2,5-diones active as enzyme aldose reductase inhibitors

摘要: The invention provides various medical compositions for use in treating or preventing certain of the side effects diabetes galactosemia. active ingredients are selected from a series novel aldose reductase inhibitory spiro-linked pyrrolidine-2,5-diones general formula: ##STR1## pharmaceutically acceptable salt, non-toxic, biodegradable precursor thereof. Processes production these compounds also provided. A particular compound suitable as an ingredient is spiro[pyrrolidine-3,9'-xanthene]-2,5-dione.