Novel Approaches in Hypertension Treatment - Modulation of the Sympathetic Overactivity

摘要: Arterial hypertension is the leading cause of mortality in world [1]. It estimated that 25 to 35 % modern populations suffer from this condition [2-4]. Hypertension major risk factor for most common cardio vascular diseases which are a morbidity and mortality. Depending on stage hypertension, it dramatically increases individual heart failure, attack, stroke or chronic kidney failure if not treated adequately [5]. Since usually directly linked specific symptoms, one insufficiently population with only 10-20 patients controlled blood pressure levels [4]. prevalence going increase within next decades. Aging contribute significantly trend [6]. Due its impact public health, already burden societies [7]. New strategies treatment options have be evaluated order slow prevent rise related This chapter focuses role sympathetic nervous system pathogenesis hypertension. After almost half decade minor advancements field, overactivity has been recognized as contributor [8]. Many secondary causes can activity lead Beyond initial contribution, sustain Therefore plays acute Understanding mechanisms involved regulation currently novel approaches treatment.