An illustration of the advantages of efficient statistical methods for RFLP analysis in forensic science.

摘要: The debate about the statistics of DNA profiling in forensic science casework has been carried out mainly from perspective which is generally known as "match/binning." This approach an initial appeal because its apparent conceptual simplicity. However, simplicity illusory it encourages misconceptions obscure essential issues. exemplified a recent report National Research Council, places great emphasis on need for conservative estimation relative frequencies while missing point that power RFLP technology cannot be realized if matching stage inefficient. Our to problem one-stage rather than two-stage process, by means one function--the likelihood ratio--which determines evidential strength. paper describes experiments have assess method and compares with match/binning methodology. Tests gauging effects between-probe dependence are included, results complementing those Risch Devlin.