Mathematical analysis and digital simulation of the respiratory control system.

作者: F S Grodins , J Buell , A J Bart

DOI: 10.1152/JAPPL.1967.22.2.260

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摘要: Abstract : The report expresses the basic material balance relationships for lung-blood-tissue gas transport and exchange system in a set of differential- difference equations containing number dependent time delays. Additional define chemical details acid-base buffering, concentration equilibria, blood flow behavior. Finally, control function is included defining dependence ventilation upon CSF (H(+)), arterial (H(+)) PO2 at carotid chemoceptors. A Fortran program was written convenient digital simulation responses to wide variety forcings, including CO2 inhalation, hypoxia sea level, altitude hypoxia, metabolic disturbances balance. Both dynamic steady-state behavior model were reasonably realistic.

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