Are right-sided colectomies for neoplastic disease at increased risk of primary postoperative ileus compared to left-sided colectomies? A coarsened exact matched analysis

摘要: The objective of this study was to determine whether right-sided colectomies (RC) were associated with a higher incidence primary postoperative ileus (pPOI) compared left-sided (LC). Patients who underwent elective colectomy for neoplastic disease between 2012 and 2016 identified using the American College Surgeons National Surgical Quality Improvement Program database. RC LC defined as having an ileocolic or colocolic/colorectal anastomosis, respectively. Coarsened Exact Matching (CEM) used balance two groups (1:1) on important confounders. association type pPOI, POI in absence intra-abdominal sepsis, then assessed multiple logistic regression analysis matched data. Of 40,636 patients disease, 15,231 25,405 LC. After CEM, 12,949 remained each group, all confounders well balanced. pPOI group (11.5% vs. 8.8%, p < 0.001). On regression, 35% odds developing (OR 1.35, 95% CI 1.25–1.47). also increased risk NSQIP-defined major morbidity 1.10, 1.01–1.20), 30-day readmission 1.16, 1.06–1.27), length stay (β = 0.16 days, 0.11–0.22). is more common after than Future research should aim at better understanding pathophysiology behind identifying interventions mitigate population.