Diagnostic and prognostic utility of an inexpensive rapid on site malaria diagnostic test (ParaHIT f) among ethnic tribal population in areas of high, low and no transmission in central India

摘要: Malaria presents a diagnostic challenge in most tropical countries. Rapid detection of the malaria parasite and early treatment infection still remain important goals disease management. Therefore, performance characteristics new indigenous ParaHIT f test (Span Ltd, Surat, India) was determined among ethnic tribal population four districts different transmission potential central India to assess whether this rapid (RDT) could be widely applied as tool control malaria. Beyond diagnosis, logical utilization RDTs is monitor outcome. A finger prick blood sample collected from each clinically suspected case prepare smear for testing with RDT after taking informed consent. The smears were read by an experienced technician blinded results clinical status subjects. figures specificity, sensitivity, accuracy predictive values calculated using microscopy gold standard. prevalence estimated parallel provide evidence type high, low or no study area. Analysis revealed (pooled data all epidemiological settings) that overall specificity >90% areas endemicity. While, useful confirm diagnosis symptomatic cases P. falciparum infection, persistence antigen leading false positives even clearance asexual parasitaemia has limited its utility prognostic tool. showed easy use, reliable cheap. Thus appropriate use field paramedical staff when laboratory facilities are not available thus likely contribute greatly effective resource poor