Magnetic Techniques for Rapid Detection of Pathogens

作者: Keat Ghee Ong , Yousef Haik , Reyad Sawafta , Irina Ciubotaru , Ahmad Qablan

DOI: 10.1007/978-0-387-75113-9_17

关键词:

摘要: In situations of widespread infectious disease an action that might result, the rapid diagnosis pathogenic states will assist first responders in implementing prompt treatments, a huge reduction number illnesses and deaths. Currently available detection/diagnostic procedures are either time-consuming (8–48 h) require enrichment culturing bacteria before testing, or provide only qualitative results. Magnetic immunoassay technology appears to have particularly superior performance over other immunodetection methods. A typical magnetic entails capture part detection part, between which target is immobilized. The consists particles functionalized from sample. immobilized then sandwiched complexes subjected process accurate results, most time matter minutes. Another important advantage sensitive confers reduced volume samples reagents needed. This chapter discusses elements associated with specifically designed for pathogens. presents review different techniques used synthesis encapsulation particles, as well strategies immobilization targeted pathogen. Several separation also discussed.

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