作者: Stephen W. Patrick , Robert E. Schumacher , Brian D. Benneyworth , Elizabeth E. Krans , Jennifer M. McAllister
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摘要: Context Neonatal abstinence syndrome (NAS) is a postnatal drug withdrawal primarily caused by maternal opiate use. No national estimates are available for the incidence of use at time delivery or NAS. Objectives To determine NAS and antepartum to characterize trends in health care expenditures associated with between 2000 2009. Design, Setting, Patients A retrospective, serial, cross-sectional analysis nationally representative sample newborns The Kids' Inpatient Database (KID) was used identify International Classification Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) code. Nationwide Sample (NIS) mothers using diagnosis related groups vaginal cesarean deliveries. conditions were identified ICD-9-CM codes. described as an annual frequency per 1000 hospital births. Missing charges ( Main Outcome Measures Incidence use, charges. Results separate years (2000, 2003, 2006, 2009) discharge data included 2920 9674 unweighted discharges 987 4563 diagnosed within sets including 784 191 1.1 million children 816 554 879 910 all ages delivering (NIS). Between 2009, among increased from 1.20 (95% CI, 1.04-1.37) 3.39 3.12-3.67) births year (P trend Conclusion substantial increase United States observed, well