Hipovitaminosis D y obesidad mórbida: efectos de la cirugía bariátrica

摘要: Los datos disponibles sobre el estado de la vitamina D en paciente con obesidad morbida son escasos hasta fecha y poco clarificantes, ya que casi siempre se ha relacionado esta insuficiencia cirugia bariatrica, sin considerar hipovitaminosis pueda preceder a cirugia. En este sentido, los pacientes no sometidos existen mecanismos patofisiologicos han deficit D, incluyendo control negativo regeneracion sintesis hepatica 25(OH) Vitamina disminucion exposicion ultravioleta solar baja biodisponibilidad estos pacientes. Por otra parte, asociacion deficiencia hiperparatiroidismo secundario sido descrito tratados bariatrica previa. estudios realizados Tesis sugieren previa parece influir significativamente dicho efecto. Estos van contra creencia establecida relacion como una las complicaciones mas habituales e indican mayoria tipo cirugia, es previo esta. En conclusion, teniendo cuenta elevada prevalencia del morbilidad asociada al mismo disponibilidad tratamiento eficaz economico que, ademas, revierten situacion, recomendable monitorizacion niveles sericos calcio, fosfato grave instaurar suplementacion calcio aquellos presenten deficit. There is scarce and flawed data regarding vitamin status in morbidly obese patients. More often than not, deficits have been linked with bariatric surgery not considering that the may well precede surgery. Moreover, there are several patho-physiological mechanisms described non-surgical patients which partially explain including negative feedback on hepatic 25-OH-Vitamin synthesis, sunlight underexposure diminished bio-availability of Vitamin due to enhanced uptake by adipose tissue. On other hand, association between secondary hyperparathyroidism has reported prior after The studies carried out this Thesis suggest unlikely cause deficits. This latter line thought contradicts established health-belief stating hypovitaminosis was frequently encountered indicates vast majority undergoing these procedures, preceded surgery. In taken into account elevated prevalence patients, its associated co-morbidity efficacy low-cost treatment restore normal serum values 25 (OH) it seems advisable recommend routine monitoring calcium, phosphorus, 25-OH-vitamin levels implement calcium supplementation whenever necessary.