The Grueneberg ganglion of the mouse projects axons to glomeruli in the olfactory bulb.
作者： Stefan H. Fuss , Masayo Omura , Peter Mombaerts
DOI: 10.1111/J.1460-9568.2005.04468.X
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摘要: First described in 1973, the Grueneberg ganglion (GG) is an arrow-shaped neuronal structure at anterior end of nasal cavity. It lines both sides septum, within vestibule, close to opening naris. The functions GG and pattern projections brain are not known. Here, we report that neurons mouse express olfactory marker protein, which normally expressed mature or vomeronasal sensory neurons. approx. 500 cells each arranged several densely packed cell clusters. Individual give rise single axons, fasciculate form a nerve bundle projects caudally. axons terminate glomeruli bulb, one two large associated with semicircle up 10 smaller, somewhat diffusely organized surround most part accessory bulb. Development starts around embryonic day 16 appears be completed birth; numbers then undergo minor decrease during postnatal development. strategic location GG, expression axonal particular locations bulb early development suggest this performs specific chemosensory neonatal stages.
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