作者: Jonathan Picker , Saumya Jamuar , Shalendra Porwal , Sumit Jamuar , Kushagra Sharma
DOI:
关键词:
摘要: The present invention relates generally to methods, algorithms, kits and systems for assessing health, diagnosing disease generating recommendations using SNV markers specific a cohort. A genetic sample of an individual is assayed genotyping assay identify at least one SNV. may be computer analysis database, nucleic acid microarray or PCR assay. identified can compared with database plurality risk SNVs, which are associated state pathological condition, including pharmacological sensitivity resistance. factor (GRF) calculated weighted score. GRF used determine the level disease. matrix generated profile cohort physiologic data. user allowed input genomic data, generate recommendations. In another aspect, analytical tool analyze relate data individual's phenotype across multiple dimensions such as his her age, family, ethnicity, environment current scientific understanding. enables specify sequence well feed in along family's entered then population list disorders. This overlaid against family confirm disorders identified. real time report updated on provide relevant information users.