Intramolecular oxidative palladium-catalyzed diamination reactions of alkenyl sulfamates: an efficient synthesis of [1,2,5]thiadiazolo-fused piperazinones
作者： Ugo Chiacchio , Gianluigi Broggini , Roberto Romeo , Silvia Gazzola , Maria A. Chiacchio
DOI: 10.1039/C6RA13141G
关键词:
摘要: A palladium-catalyzed diamination domino process of sulfamates arising from glycine allylamides is reported. The reaction leads to the formation [1,2,5]thiadiazolo-fused piperazinones. essential feature synthetic route use PdCl2(MeCN)2/CuBr2, as a catalytic system which promotes second amination process, leading bicycle ring-fused compounds in good yields.
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