Solid dosage form containing quinazoline derivative
作者： Sakuma Satoshi , Yokoyama Reiji , Tanaka Hironori , Aikawa Shohei
DOI:
关键词:
摘要: The present invention provides a formulation containing the compound represented by formula (I) or pharmaceutically acceptable salt thereof, their crystals, with light-stabilizing substance and polymer, particularly one more of titanium oxide talc used as substance, hypromellose which hardly increase amount related substances, is colored under light irradiation.
lens.org 参考文章(13)
Naoto Konya, Gohfu Suzukamo, Yukio Higashi Apt. No. Yoneyoshi, Process for isomerization of oxime ethers ,(1990)
David M. Crowe, Andrew Simon Craig, Michael Millan, Quinazoline ditosylate anhydrate forms ,(2008)
Yusuke Suzuki, Gakuji Kiyonaka, Yoshihiro Furuya, Medicinal preparation containing 5-methyl-1-phenyl-2-(1h)-pyridone as active ingredient ,(2002)
Kenji Matsuo, Masami Takayama, Aiko Omori, Takeshi Endo, Masaharu Kume, Naoki Omori, Quinazoline derivative having tyrosine kinase inhibitory activity ,(2006)
Yasuo Kokai, Jeffrey N. Myers, Takuro Wada, Valerie I. Brown, Charles M. LeVea, James G. Davis, Kunio Dobashi, Mark I. Greene, Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts Cell. ,vol. 58, pp. 287- 292 ,(1989) , 10.1016/0092-8674(89)90843-X
Zilberstein A, Mundy Gr, Yoneda T, Reddy Kb, Tandon Ak, Osborne Ck, Mangold Gl, Inhibition of breast cancer cell growth in vitro by a tyrosine kinase inhibitor. Cancer Research. ,vol. 52, pp. 3636- 3641 ,(1992)
Frank Glaxosmithkline Roschangar, Mark J. Glaxosmithkline Sacchetti, Martin H. Glaxosmithkline Osterhout, Michael S. Glaxosmithkline Mcclure, Quinazoline ditosylate salt compounds ,(2001)
Alexander Levitzki, Paul E. Persons, Asher Zilberstein, Gregory R. Mundy, Alfred P. Spada, Toshiyuki Yoneda, Ray M. Lyall, Maria M. Alsina, The antiproliferative effects of tyrosine kinase inhibitors tyrphostins on a human squamous cell carcinoma in vitro and in nude mice Cancer Research. ,vol. 51, pp. 4430- 4435 ,(1991)
David M. Crowe, Andrew Simon Craig, Michael Millan, Quinazoline anhydrate forms ,(2008)
Hiroyuki Kawashima, Masato Kozaki, Yoshio Tanizawa, Pharmaceutical preparation having excellent photostability ,(2006)