Antioxidant Activity of 3-[N-(Acylhydrazono)ethyl]-4-hydroxy-coumarins
作者： Antigoni Kotali , Despina Nasiopoulou , Constantinos Tsoleridis , Philip Harris , Christos Kontogiorgis
DOI: 10.3390/MOLECULES21020138
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摘要: A series of 3-acylhydrazono-4-hydroxycoumarins were synthesized via condensation 3-acetyl-4-hydroxycoumarin with appropriate hydrazides. The structures the newly-synthesized compounds characterized by spectral and elememental analysis or HRMS measurements. Their antioxidant properties evaluated using scavenging effects on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical as well inhibition lipid peroxidation. Moreover, their ability to inhibit in vitro soybean lipoxygenase has been investigated. They found be capable rapid inactivation alkylperoxy radicals.
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