Issues in the management of contacts of patients with active pulmonary tuberculosis

摘要: The evidence regarding the transmission of tuberculosis and risk infection disease in several specific clinical situations has been reviewed. There is considerable epidemiologic that contagiousness not an all-or-nothing phenomenon affected by factors, only one which bacteriologic status patient’s sputum. Although untreated smear negative, culture positive patients are less contagious on average, they still may transmit to their close casual contacts. Compared with contacts tuberculin conversion, persons who already have much lower developing active after exposure, prior BCG vaccination at somewhat risk. Preventive therapy will be benefit, but should recommended for heavily exposed or immune compromised. Epidemiologic studies using RFLP techniques could provide more precise answers questions this review.