Triton X-100 as a channel-forming substance in artificial lipid bilayer membranes☆
作者： P. Schlieper , E. De Robertis
DOI: 10.1016/0003-9861(77)90343-5
关键词:
摘要: The nonionic detergent Triton X-100, introduced into artificial membranes of various lipid compositions, induced current fluctuations that may correspond to the formation channels across bilayer. Independently used, these vary in amplitude between 1 and 4·10−10, Ω−1, show a strong dependence on applied voltage, are selective for cations sequence Rb+ > K+ Na+ Li+. These results discussed relation chemical structure X-100 molecule.
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sci-hub.se 参考文章(22)
G.P. Brierley, M. Jurkowitz, A.J. Merola, K.M. Scott, Ion transport by heart mitochondria. XXV. Activation of energy-linked K + uptake by non-ionic detergents. Archives of Biochemistry and Biophysics. ,vol. 152, pp. 744- 754 ,(1972) , 10.1016/0003-9861(72)90270-6
S.B. Hladky, D.A. Haydon, Ion transfer across lipid membranes in the presence of gramicidin A Biochimica et Biophysica Acta (BBA) - Biomembranes. ,vol. 274, pp. 294- 312 ,(1972) , 10.1016/0005-2736(72)90178-2
S Clarke, The size and detergent binding of membrane proteins. Journal of Biological Chemistry. ,vol. 250, pp. 5459- 5469 ,(1975) , 10.1016/S0021-9258(19)41204-0
G.P. Brierley, M. Jurkowitz, K.M. Scott, K.M. Hwang, A.J. Merola, Activation of energy-linked K+ accumulation in isolated heart mitochondria by non-ionic detergents Biochemical and Biophysical Research Communications. ,vol. 43, pp. 50- 57 ,(1971) , 10.1016/S0006-291X(71)80084-0
Dolly Ghosh, M.A. Williams, J. Tinoco, The influence of lecithin structure on their monolayer behavior and interactions with cholesterol Biochimica et Biophysica Acta. ,vol. 291, pp. 351- 362 ,(1973) , 10.1016/0005-2736(73)90488-4
Thomas E. Andreoli, THE STRUCTURE AND FUNCTION OF AMPHOTERICIN B-CHOLESTEROL PORES IN LIPID BILAYER MEMBRANES Annals of the New York Academy of Sciences. ,vol. 235, pp. 448- 468 ,(1974) , 10.1111/J.1749-6632.1974.TB43283.X
S. J. Singer, G. L. Nicolson, The Fluid Mosaic Model of the Structure of Cell Membranes Science. ,vol. 175, pp. 720- 731 ,(1972) , 10.1126/SCIENCE.175.4023.720
Moisés Eisenberg, James E. Hall, C. A. Mead, The nature of the voltage-dependent conductance induced by alamethicin in black lipid membranes. The Journal of Membrane Biology. ,vol. 14, pp. 143- 176 ,(1973) , 10.1007/BF01868075
B. De Kruijff, R.A. Demel, Polyene antibiotic-sterol interactions in membranes of Acholeplasma laidlawii cells and lecithin liposomes. III. Molecular structure of the polyene antibiotic-cholesterol complexes Biochimica et Biophysica Acta. ,vol. 339, pp. 57- 70 ,(1974) , 10.1016/0005-2736(74)90332-0
H. Van Zutphen, A.J. Merola, G.P. Brierley, David G. Cornwell, The interaction of nonionic detergents with lipid bilayer membranes. Archives of Biochemistry and Biophysics. ,vol. 152, pp. 755- 766 ,(1972) , 10.1016/0003-9861(72)90271-8