Flow fine synthesis with heterogeneous catalysts
作者： Koichiro Masuda , Tomohiro Ichitsuka , Nagatoshi Koumura , Kazuhiko Sato , Shū Kobayashi
DOI: 10.1016/J.TET.2018.02.006
关键词:
摘要: Abstract In the past few decades, organic reactions under flow conditions have attracted increasing attention. Flow a number of advantages over batch in terms environmental compatibility, efficiency, and safety. particular, with heterogeneous catalysts that yield desired products without significant levels by-product formation can enable purification processes to be avoided. This feature allow assembled multi-step continuous manner for synthesis complex molecules. These new techniques opened up approaches fine chemicals are expected play prominent role future chemical manufacturing processes. this context, review aims summarize recent developments continuous-flow chemicals.
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