作者: Agnieszka Wyszyńska , Łaniewski , Majewski , Elżbieta Katarzyna Jagusztyn-Krynicka , Lis
DOI: 10.2147/VDT.S33742
关键词:
摘要: Campylobacter jejuni is a major food-borne pathogen, causing gastroenteritis worldwide. Chickens are considered to be one of the most common sources human C. infection in developed countries. CjaD/Pal protein (annotated as Cj0113 strain NCTC11168) highly immunogenic, membrane-located antigen, conserved among different strains, with potential provide broad protection against colonization. The present study examines immunogenicity and general efficacy avirulent S. enterica sv. Typhimurium ∆crp ∆cya expressing CjaD chicken vaccine high copy number plasmid pYA3341 Asd + was used