Low BMI at age 20 years predicts gestational diabetes independent of BMI in early pregnancy in Japan: Tanaka Women’s Clinic Study

摘要: Diabet. Med. 30, 70–73 (2013) Abstract Aims  Maternal obesity and weight gain since early adulthood are known predictors of gestational diabetes in Western countries. However, their impact has not been evaluated well Asia, where mean BMI levels generally lower than We therefore examined the associations at age 20 years change with risk Japanese pregnant women. Methods  Six hundred twenty-four consecutive women without recognized before pregnancy, whose initial obstetric clinic visit was 13 weeks’ gestation, were prospectively observed. Weight self-reported. Baseline height measurements obtained visit. Multivariate logistic regression analysis estimated incident for 20 years. Results  Twenty-eight developed diabetes. By multivariate that adjusted maternal age, parity baseline BMI, we observed a statistically significant inverse association between incidence (odds ratio 0.68, 95% CI 0.51–0.92). Similarly, when assessed 20 years, parity, associated an increased 1.26, 95% CI 1.03–1.53). When focused on threshold diabetes, less 18 kg/m2 had 6.30-fold (2.26–17.59) greater both or more 1.85. Conclusions  Both low significantly