Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons
作者： Sean P. Cregan , Jason G. MacLaurin , Constance G. Craig , George S. Robertson , Donald W. Nicholson
DOI: 10.1523/JNEUROSCI.19-18-07860.1999
关键词:
摘要: … First, we demonstrate that p53-induced apoptosis in cerebellar granule neurons results in a strong activation of caspase-3. Second, caspase-3 activity and the subsequent cell death …
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