Emerging importance of ALK in neuroblastoma.

作者: Anna M. Azarova , Gargi Gautam , Rani E. George

DOI: 10.1016/J.SEMCANCER.2011.09.005

关键词:

摘要: … ALK-mediated signaling in this tumor. This review addresses many of the current issues surrounding the role of ALK in … for clinically effective targeted treatments based on ALK inhibition. …

参考文章(74)
Karen Pulford, Laurence Lamant, Stephan W. Morris, Lisa H. Butler, Katrina M. Wood, David Stroud, Georges Delsol, David Y. Mason, Detection of Anaplastic Lymphoma Kinase (ALK) and Nucleolar Protein Nucleophosmin (NPM)-ALK Proteins in Normal and Neoplastic Cells With the Monoclonal Antibody ALK1 Blood. ,vol. 89, pp. 1394- 1404 ,(1997) , 10.1182/BLOOD.V89.4.1394
Scott J Rodig, Geoffrey I Shapiro, Crizotinib, a small-molecule dual inhibitor of the c-Met and ALK receptor tyrosine kinases. Current opinion in investigational drugs. ,vol. 11, pp. 1477- 1490 ,(2010)
Pablo Perez-Pinera, Wei Zhang, Yunchao Chang, Jose Antonio Vega, Thomas F. Deuel, Anaplastic lymphoma kinase is activated through the pleiotrophin/receptor protein-tyrosine phosphatase β/ζ signaling pathway : An alternative mechanism of receptor tyrosine kinase activation Journal of Biological Chemistry. ,vol. 282, pp. 28683- 28690 ,(2007) , 10.1074/JBC.M704505200
Camilla Englund, Christina E. Lorén, Caroline Grabbe, Gaurav K. Varshney, Fabienne Deleuil, Bengt Hallberg, Ruth H. Palmer, Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion Nature. ,vol. 425, pp. 512- 516 ,(2003) , 10.1038/NATURE01950
Ruth H. Palmer, Emma Vernersson, Caroline Grabbe, Bengt Hallberg, Anaplastic lymphoma kinase: signalling in development and disease Biochemical Journal. ,vol. 420, pp. 345- 361 ,(2009) , 10.1042/BJ20090387
Willy G. Dirks, Silke Fähnrich, Yvonne Lis, Elisabeth Becker, Roderick A.F. MacLeod, Hans G. Drexler, Expression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell lines International Journal of Cancer. ,vol. 100, pp. 49- 56 ,(2002) , 10.1002/IJC.10435
Laurence Lamant, Karen Pulford, Daniela Bischof, Stephan W. Morris, David Y. Mason, Georges Delsol, Bernard Mariamé, Expression of the ALK tyrosine kinase gene in neuroblastoma. American Journal of Pathology. ,vol. 156, pp. 1711- 1721 ,(2000) , 10.1016/S0002-9440(10)65042-0
Shawn P. Hurley, Douglas O. Clary, Valerie Copie, Frances Lefcort, Anaplastic lymphoma kinase is dynamically expressed on subsets of motor neurons and in the peripheral nervous system. The Journal of Comparative Neurology. ,vol. 495, pp. 202- 212 ,(2006) , 10.1002/CNE.20887
Elena Ardini, Maria Menichincheri, Luisa Rusconi, Paola Magnaghi, Paolo Orsini, Nilla Avanzi, Andrea Lombardi Borgia, Marcella Nesi, Tiziano Bandiera, Gianpaolo Fogliatto, Jay A. Bertrand, Roberto T. Bossi, M. Beatrice Saccardo, Crystal Structures of Anaplastic Lymphoma Kinase in Complex with ATP Competitive Inhibitors. Biochemistry. ,vol. 49, pp. 6813- 6825 ,(2010) , 10.1021/BI1005514
Erica L. Carpenter, Elizabeth A. Haglund, Adrian K. Chow, James G. Christensen, John M. Maris, Yael P. Mosse, Abstract 742: Mechanisms of resistance to small molecule inhibition of anaplastic lymphoma kinase in human neuroblastoma Cancer Research. ,vol. 71, pp. 742- 742 ,(2011) , 10.1158/1538-7445.AM2011-742