Pulmonary Artery Pressure Changes during Ethanol Embolization Procedures to Treat Vascular Malformations: Can Cardiovascular Collapse be Predicted?

摘要: PURPOSE Ethanol has been used for embolization of vascular malformations. Cardiovascular collapse, although rare, reported, occurring immediately to a few hours after ethanol embolization. The pathophysiology theoretically attributed direct toxicity the cardiac conduction system or pulmonary artery (PA) vasospasm leading cardiovascular collapse. Because collapse in one patient at authors' institution, it was standard care time this study monitor pressures during This conducted clarify effect on PA pressure these procedures. METHODS Data from 92 procedures performed 56 patients with malformations between May 2001 and 2003 are reported. noninvasive cuff systemic were recorded before each injection also entire procedure. Upper limit volume drawn 1 mL/kg. Simple multiple linear regression analyses done factors affecting changes blood pressure. RESULTS For injection, averaged 3.1 mL per injection. systolic increased by 2.3 1.0 mm Hg, respectively. Amount injected predictive change During procedure, an average 11.6 5 Hg. Change strong predictor of, weak CONCLUSION mild rise correlated strongly minor elevation throughout which authors believe is related pain causing sympathetic stimulation, even when under general anesthesia. minimal does not elucidate cause rare complication