Outcomes and risk factors of postoperative hepatic dysfunction in patients undergoing acute type A aortic dissection surgery.

摘要: Background Postoperative hepatic dysfunction (HD) increases the morbidity and mortality risk after cardiac surgery; however, only a few studies have specifically focused on acute type A aortic dissection (AAAD) surgery. We explored possible factors outcomes of early postoperative HD in patients with AAAD undergoing Methods All who underwent surgery at our institution from April 2015 to 2017 were retrospectively evaluated. model for end-stage liver disease (MELD) score was used define HD. Independent determined by multivariate logistic analysis. Results Two hundred fifteen met inclusion criteria. The incidence rate 60.9%, in-hospital 16.8%. Patients high MELD had longer mechanical ventilation time, durations intensive care unit (ICU) stay, higher mortality. During period, complicated needed continuous renal replacement therapy (CRRT), reintubation, tracheostomy, blood transfusion more frequently. Aortic cross clamp (ACC) time [per 10 min higher; odds ratio (OR): 1.216, 95% confidence interval (CI): 1.017-1.454, P=0.032], leucocytes (per 2×109/L OR: 1.161, CI: 1.018-1.324, P=0.026), respiratory (OR: 3.176, 1.293-7.803, P=0.012), low output syndrome (LCOS) 12.663, 1.432-111.998, P=0.022) independent associated Conclusions prolongs ICU is increased among undergo Several are score.