Long-Chain (n-3) Fatty Acid Intake and Risk of Cancers of the Breast and the Prostate: Recent Epidemiological Studies, Biological Mechanisms, and Directions for Future Research

作者: Paul D. Terry , Jennifer B. Terry , Thomas E. Rohan

DOI: 10.1093/JN/134.12.3412S

关键词:

摘要: The association between dietary (n-3) fatty acids and hormone-responsive cancers continues to attract considerable attention in epidemiological, clinical, experimental studies. We previously reviewed the epidemiological literature on long-chain eicosapentaenoic acid docosahexaenoic acid. concluded that compelling evidence from ecological studies, animal models, mechanistic experiments vitro was not supported clearly by available data. To various degrees, studies published more recently attempted address some of methodological limitations plaguing earlier using validated questionnaires, examining specific their interrelationships, adjusting estimates for a wider range potentially confounding factors than previous In this review, our aim update review with results recent discuss possible biological mechanisms directions future research.

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