5-substituted iminothiazines and their mono-and dioxides as bace inhibitors, compositions, and their use
作者： Duane A. Burnett , Wen-Lian Wu , Andrew W. Stamford , Thavalakulamgara K. Sasiskumar , Jared N. Cumming
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摘要: The present invention discloses certain iminothiazine compounds and mono- dioxides thereof, including Formula (I): tautomers stereoisomers pharmaceutically acceptable salts of said compounds, stereoismers, wherein each variables shown in the formula are as defined herein. may be useful BACE inhibitors and/or for treatment prevention various pathologies related thereto. Pharmaceutical compositions comprising one or more such (alone combination with other active agents), methods their preparation uses, Alzheimer's disease, also disclosed.
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