作者: Frederick Koster
DOI: 10.2217/FVL.13.83
关键词:
摘要: The threat of a virulent, highly transmissible pandemic virus has motivated an escalating research effort to identify the genotypes animal viruses that cross over into human population (animal–human transmission) and sustain human–human transmission. In addition pursuit viral genotype, greater understanding host-virus phenotype infectiousness, transmissibility susceptibility will be required. This review examines experimental transmission influenza for insights Transmission is viewed as sequential steps must pass critical thresholds achieve ultimately survival in host. particular, quantitative models replication efficiency, airway load, exhaled aerosol environmental host likely yield important insights. Computational modeling enhance model data, well guide...