Catalytic enantioselective addition of methyltriisopropoxititanium to aldehydes
作者： Marcos Veguillas , Ricard Solà , M. Ángeles Fernández-Ibañez , Beatriz Maciá
DOI: 10.1016/J.TETASY.2016.06.001
关键词:
摘要: An efficient catalyst for the enantioselective synthesis of chiral methyl carbinols from aldehydes is presented. The system uses methyltriisopropoxytitanium as a nucleophile and readily available binaphthyl derivative ligand. methylation both aromatic aliphatic proceeds with good yields high enantioselectivities under mild conditions.
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