Gradual release medicine carrier

作者: Abraham S

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摘要: A medicament carried within a perforate or semipermeable shell is gradually released, as by dissolution into body fluids, to provide effective therapy with reduced concentration and dosage. The may be in dry powdered form. For treatment of the eye, carrier comprises capsule less than 1 millimeter diameter which placed conjunctival sac mounted contact lens. colored for easy location removal, absorbable body, swell allow washout tears. glaucoma treatment, milligram pilocarpine phospholine single sustained release an adequate daily In another embodiment soft lens itself serve medicine containing carrier. burn, ulcer, wound planar configuration incorporated film forming spray comprising many minute particles capsules each medicament. resultant will protect tissue from exposure, medication, eliminate need removal concomitant damage newly formed granulation tissue.

参考文章(6)
Stephen R. Waltman, Herbert E. Kaufman, Use of hydrophilic contact lenses to increase ocular penetration of topical drugs. Investigative Ophthalmology & Visual Science. ,vol. 9, pp. 250- 255 ,(1970)
Takeru Higuchi, Drug-delivery device ,(1970)
Antonio R. Gasset, Herbert E. Kaufman, Therapeutic Uses of Hydrophilic Contact Lenses American Journal of Ophthalmology. ,vol. 69, pp. 252- 259 ,(1970) , 10.1016/0002-9394(70)91287-0
Thomas H Shephered, Francis E Gould, Zero order release constant elution rate drug dosage ,(1970)
Sedlácek J, Possibility of the application of ophthalmic drugs with the use of gel contact lenses Ceskoslovenská oftalmologie. ,vol. 21, pp. 509- 512 ,(1965)