Haloperidol parenterally for treatment of vomiting and nausea from gastrointestinal disorders in a group of geriatric patients: double-blind, placebo-controlled study.

摘要: Twenty-eight geriatric residents of a nursing home participated in double-blind study to compare the 12-hour therapeutic effectiveness single intramuscular injection (1.0 mg) haloperidol with that placebo for relief vomiting and nausea due gastrointestinal disorders. Significantly fewer episodes occurred group than group. Nausea also was less frequent After four hours, symptoms recurred much more often Global evaluations showed significantly greater number patients improved markedly did those given placebo. There were no clinically significant changes vital signs throughout In 1 patient pulse rate increased; otherwise adverse reactions reported this Thus, nursing-home population who experienced disorders, administered parenterally proved be safe highly effective antiemetic agent.