Screen-detected breast cancer compared to symptomatic presentation: an analysis of surgical treatment and end-points of effective mammographic screening.

摘要: Background: Mammographic screening has been shown to reduce mortality from breast cancer and offer more opportunity for conservation surgery (BCS). The minimum standards (or surrogate end-points) that need be achieved by a programme if it is have derived the Two County Study. Three end-points can used gauge quality of service are 50% identified infiltrating cancers should < 15 mm; at least 30% grade 3 70% screen-detected negative axillary dissection. present study assesses these effective in an urban population referred Strathfield Breast Centre (TSBC). surgical treatment one group women with BreastScreen New South Wales (NSW)-detected (screen group) were compared all other, mostly symptomatic, referrals (symptom group). problems current pattern acceptance mammographic TSBC’s referral area discussed. Methods: A prospective non-randomized was done via analysis database (TSBC). Results: There 224 screen 657 symptom group. mean tumour size 18.1 mm 22.1 significantly small invasive (< mm) (58%) (33%; P 0.001). In there low-grade tumours but 16% (P = 0.009). patients who underwent dissection, significant difference node negativity, being 72% 59% 0.003). 64% had BCS 51% 0.002). Conclusions: These met NSW TSBC despite biases involved which could lessen effectiveness programme. This crudely translated into reduction selection lead time bias taken account evaluation data. greater chance