Excitatory and inhibitory postsynaptic currents of the superior salivatory nucleus innervating the salivary glands and tongue in the rat.
作者： Yoshihiro Mitoh , Makoto Funahashi , Motoi Kobashi , Ryuji Matsuo
DOI: 10.1016/J.BRAINRES.2003.11.053
关键词:
摘要: The excitatory and inhibitory synaptic inputs to parasympathetic preganglionic neurons in the superior salivatory (SS) nucleus were investigated brain slices of neonatal (4-8 days old) rat using whole-cell patch-clamp technique. SS innervating submandibular sublingual salivary glands lingual artery anterior region tongue identified by retrograde transport a fluorescent tracer. Whole-cell currents evoked electrical stimulation tissue surrounding cell. These postsynaptic completely abolished antagonists for N-methyl-D-aspartate (NMDA) glutamate, non-NMDA gamma-aminobutyric acid type A (GABAA), glycine receptors, suggesting that receive glutamatergic excitatory, GABAergic glycinergic inputs. In glands, ratio NMDA component total current (EPSC) was larger than component. This profile reversed tongue. GABAA IPSC (IPSC). decay time constants slower those glycine. characteristics may be involved determining firing properties
elsevier.com
sci-hub.se 参考文章(40)
R. A. Travagli, R. A. Gillis, C. D. Rossiter, S. Vicini, Glutamate and GABA-mediated synaptic currents in neurons of the rat dorsal motor nucleus of the vagus. American Journal of Physiology-gastrointestinal and Liver Physiology. ,vol. 260, ,(1991) , 10.1152/AJPGI.1991.260.3.G531
C.D. Stern, Handbook of Chemical Neuroanatomy Neurochemistry International. ,vol. 8, pp. 443- 444 ,(1986) , 10.1016/0197-0186(86)90021-5
F. Jacoby, C. R. Leeson, The postnatal development of the rat submaxillary gland. Journal of Anatomy. ,vol. 93, pp. 201- 216 ,(1959)
嘉男 中村, Barry J. Sessle, Neurobiology of Mastication - from Molecular to Systems Approach Elsevier. ,(1999)
Kensuke Futai, Masayoshi Okada, Kyoko Matsuyama, Tomoyuki Takahashi, None, High-Fidelity Transmission Acquired via a Developmental Decrease in NMDA Receptor Expression at an Auditory Synapse The Journal of Neuroscience. ,vol. 21, pp. 3342- 3349 ,(2001) , 10.1523/JNEUROSCI.21-10-03342.2001
H Xie, L Ziskind-Conhaim, Blocking Ca(2+)-dependent synaptic release delays motoneuron differentiation in the rat spinal cord The Journal of Neuroscience. ,vol. 15, pp. 5900- 5911 ,(1995) , 10.1523/JNEUROSCI.15-09-05900.1995
R. Matsuo, Central Connections for Salivary Innervations and Efferent Impulse Formation Karger Publishers. ,vol. 11, pp. 26- 43 ,(1999) , 10.1159/000061119
Kirsteen N. Browning, Alexander E. Kalyuzhny, R. Alberto Travagli, Opioid Peptides Inhibit Excitatory But Not Inhibitory Synaptic Transmission in the Rat Dorsal Motor Nucleus of the Vagus The Journal of Neuroscience. ,vol. 22, pp. 2998- 3004 ,(2002) , 10.1523/JNEUROSCI.22-08-02998.2002
VM Pickel, J Chan, TA Milner, Ultrastructural basis for interactions between central opioids and catecholamines. II. Nuclei of the solitary tracts The Journal of Neuroscience. ,vol. 9, pp. 2519- 2535 ,(1989) , 10.1523/JNEUROSCI.09-07-02519.1989
L. Nowak, P. Bregestovski, P. Ascher, A. Herbet, A. Prochiantz, Magnesium gates glutamate-activated channels in mouse central neurones Nature. ,vol. 307, pp. 462- 465 ,(1984) , 10.1038/307462A0