The Adrenergic System in Vascular Smooth Muscle

摘要: Adrenoceptors can be divided into three major subcategories, α1-, α2- and β-adrenoceptors, each of which has receptor subtypes. Vascular smooth muscle contractions are mediated by the actions sympathetic nerves circulating adrenaline noradrenaline at α1- α2-adrenoceptors on vascular cells, relaxations β-adrenoceptors cells. β-Adrenoceptors present endothelial cells also mediate influencing Studies basal blood pressure in knockout (KO) mice demonstrate that most important receptors control vasculature α1D-adrenoceptors α2A-adrenoceptors, mediating peripheral pressor central depressor effects, respectively. Indeed, may as targets for neurally released controlling resistance tissue flow, although this remains to established. The flow a number circulations is detailed.