Pseudo-nitzschia (Bacillariophyceae) species, domoic acid and amnesic shellfish poisoning: revisiting previous paradigms

摘要: LELONG A., HEGARET H., SOUDANT P. AND BATES S.S. 2012. Pseudo-nitzschia (Bacillariophyceae) species, domoic acid and amnesic shellfish poisoning: revisiting previous paradigms. Phycologia 51: 168-216. DOI: 10.2216/11-37 is a globally distributed diatom genus, some species of which produce (DA), the neurotoxin that causes poisoning. This toxin killed at least three humans in 1987, launching numerous studies concerning identification, distribution, ecology physiology spp. Since reviews 1998, knowledge has been gained about fate DA, including its accumulation by marine animals degradation light bacteria. Molecular techniques more precise microscopy have enabled description new 15 since 2002, ones are cryptic pseudo-cryptic. An increasing number 37 identified oceanic coastal studied laboratory culture. The sexual reproduction 14 documented. Fourteen now shown to be toxigenic, although strains not always toxic under testing conditions. biotic abiotic factors modify DA production reviewed, with focus on how discoveries changed our original hypotheses control mechanisms. Recent confirm silicate phosphate limitation trigger production. However, stress low concentrations iron or high copper newly discovered triggers, suggesting trace-metal chelation role for DA. Organic sources nitrogen (urea glutamine), as well changes pH, CO2, salinity bacterial concentration, also enhance Laboratory field sometimes give divergent results conditions conducive Gaps include further information whole genome Pseudo- nitzschia (including stages), mechanisms decline, presence absence resting stage, heterotrophic ability, impact viruses fungi, complete ecological physiological roles