摘要: 1. An Historical and Phylogenetic Perspective of Islet-Cell Development R.C. Heller, J. Jensen, O.D. Madsen, H.V. Petersen, P. Serup. 2. Glucose Signalling to Transcription Factors the Insulin Gene D. Melloul. 3. beta-Cell Dysfunction Chronic Hyperglycaemia J.L. Leahy. 4. Toxicity Pancreatic beta-cell C. Gleason, Harmon, V. Poitout, R.P. Robertson, G. Sacchi, Y. Tanaka, Phuong Oanh T. Tran. 5. The alpha-Cell Regulation Glucagon W. Knepel. 6. KATP Channel Sulfonylurea Receptor Miki, S. Seino, H. Yano. 7. Glucagon-Like Peptide-1: Insulinotropic Hormone with Potent Growth Factor Actions at Islets Langerhans G.G. Holz, C.A. Leech. 8. Communication Islet Cells: Molecules Functions Bosco, Meda. 9. Soluble Important for Pancreas Czernichow, R. Scharfmann. 10. Role Mesenchymal-Epithelial Interactions in Crisera, G.K. Gittes, A.S. Kadison, M.T. Longaker, T.S. Maldonado. 11. Homeodomain Proteins U. Ahlgren, Edlund. 12. bHLH Notch L.E. Flores, R.S. 13. Identification, Biological Functions, Contribution Human Diabetes Islet-Brain 1 C.Bonny, Waeber. 14. Pax4 Pax6 Differentiation Gruss, Xunlei Zhou. 15. Hepatocyte Nuclear Network Homeostasis M. Stoffel. 16. PDX-1 Expression M.A. Cissell, K. Gerrish, Samaras, Stein, C.V.E. Wright. 17. Mechanisms Postnatal b-Cell Mass Bonner-Weir, G.C. Weir. 18. Genetic Models Resistance: Alterations Biology C.R. Kahn, R.N. Kulkarni. 19. Clinical Consequences Defects Genes J.C. Evans, T.M. Frayling, A.T. Hattersley. 20. Pathophysiology Glut2 Mellitus B. Thorens. 21. Use a Cre-LoxP Strategy Mice Determine Cell-Specific Roles Glucokinase MODY-2 Magnuson, Postic. 22. Lines Transplantation Type Efrat. 23. Therapeutic Approaches Replacement G.M. Beattie, A. Hayek, F. Levine. Colour Figures. Index.
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