Preferential enhancement of IgE antibody formation by Bordetella pertussis.

作者: Matsunobu Suko , Tadaatsu Ogita , Hirokazu Okudaira , Yoshihiko Horiuchi

DOI: 10.1159/000231845

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摘要: Preferential enhancement of IgE antibody response was observed in BALB/c mice by the administration Bordetella pertussis with antigen (DNP-Salmonella). Correlation between B cell mitogenic activity and adjuvant action among B. pertussis, Salmonella, lipopolysaccharide Escherichia coli Ficoll examined but not found. Thymus-derived cells seemed necessary to develop since athymic nude influenced pertussis. Helper function adoptively transferred spleen enhanced immunization donor carrier presence The magnitude greatest class. results indicated that preferential formation is mediated augmentation carrier-specific helper function.

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