Non-Genomic Action of Sex Steroid Hormones

作者: Antimo Migliaccio , Gabriella Castoria , Ferdinando Auricchio

DOI: 10.1007/978-90-481-3303-1_15

关键词:

摘要: This chapter aims at giving a concise, up-to-date view of the non-genomic action sex-steroid hormones and some related aspects. It includes an overview identity receptors mediating action. To date, classical steroid are known to be principal mediators this action, although there is now evidence that G-protein coupled have similar role. Non-genomic has been separately analyzed in hormone-responsive cells (reproductive cells) non-classical (non-reproductive cells). With distinction we intend underline different biological responses induced by steroids these two cell types depending on their functions, as well low level receptor expression cells, which might explain absence transcriptional activity such cells. One section focuses reversible integration between extra-nuclear nuclear hormone Activation kinase cascades produces effects nuclei. In addition or co-activator modifications, chromatin remodeling, export, increased signaling effectors observed. The final deals with cross talk growth factor signaling, process links hormonal receptors, regulates important functions. We apologize scientists working area whose reports not mentioned extensively discussed owing space limitations.

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