Multi-step bioassays on modular microfluidic application platforms

作者: Michael Steinwand , Alexander Jung , Simone Guenther , H. Michael Wenz , Timothy G. Geiser

DOI:

关键词:

摘要: The current invention refers to a system, method and apparatus for detecting target polynucleotide in sample. It comprises first platform comprising plurality of wells; second wells, wherein the wells are fluid communications with system is closed capable transferring products from wells. Further platforms respective optional.

参考文章(19)
Thuraiayah Vinayagamoorthy, Roger Grant Hodkinson, Apparatus for multi-zone polymerase chain reaction ,(1998)
Marcy Engelstein, Ulrich Thomann, Patrick Cahill, Douglas Smith, Device for rapid dna sample processing with integrated liquid handling, thermocycling, and purification ,(2000)
Roland Zengerle, Peter Koltay, Device and method for dosing small amounts of liquid ,(2002)
Richard A. Mathies, Peter C. Simpson, Microplate sample and reagent loading system ,(1999)
Phillip W. Barth, Carol T. Schembri, William H. McAllister, Arthur Schleifer, Michael P. Caren, Method and multiple reservoir apparatus for fabrication of biomolecular arrays ,(1998)
E. Nicol Mcgruer, Yuriy M. Dunayevskiy, Paul M. Zavracky, Barry L. Karger, Frantisek Foret, Qifeng Xue, Microscale fluid handling system ,(1996)
Ian David Manger, Marc A Unger, Hou-Pu Chou, Yong Yi, Dave Fernandez, Microfluidic devices for introducing and dispensing fluids from microfluidic systems ,(2001)
Gary J Schnerr, Sheila H Dewitt, Sheldon M Kugelmass, Lin Chao, Dale R Pfost, Robert D Juncosa, Rolf E Swenson, Multiple fluid sample processor and system ,(2000)
Deborah A. Nickerson, Leroy E. Hood, Robert J. Kaiser, John Zebala, Francis Barany, A thermostable ligase mediated dna amplification system for the detection of genetic diseases ,(1991)