Toward a rationale for the PTC124 (Ataluren) promoted readthrough of premature stop codons: a computational approach and GFP-reporter cell-based assay.
作者： Laura Lentini , Raffaella Melfi , Aldo Di Leonardo , Angelo Spinello , Giampaolo Barone
DOI: 10.1021/MP400230S
关键词:
摘要: … NMD is a surveillance pathway, triggered when ribosomes … proofreading function of the ribosome, leading to insertion of a … or Ataluren, was suggested to induce ribosomal readthrough …
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