Influence of aging on oral-pharyngeal bolus transit and clearance during swallowing: scintigraphic study.

摘要: The aim of the study was to determine influence normal aging on regional transit and efficiency bolus clearance during oral pharyngeal phases swallowing. We compared scintigraphically derived oral-pharyngeal times isotope swallowing in 21 healthy aged volunteers (mean age 68 +/- 8 yr) 9 young controls 28 7.5 yr). Subjects swallowed 5- 10-ml water boluses mixed with 30 MBq 99mtechnetium tin colloid. Oral times, time, postswallow residual counts each region were from time-activity curves. Pharyngeal significantly greater than (P = 0.0008), but did not residual. Aging prolonged time 0.02), 0.0004), 0.0001). conclude that impairs swallowing, prolongs scintigraphic measures transit, increases exposure glottis bolus.