Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
作者： William R. Wolter , Mark A. Suckow , Paul J. Hall
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摘要: Disclosed are vaccines and vaccine adjuvants useful in the treatment and/or prevention of infection diseases associated with infectious pathogens, such as tetanus, well biological toxins. Also provided methods preparing an adjuvant containing adjuvant. Methods also for vaccinating/immunizing animal against other Adjuvant materials presented that prepared from extracellular matrix material. The demonstrated to enhance immunogencity pathogen antigen or toxin interest, survival immunized animal.
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Annemieke Dols, John W. Smith, Sybren L. Meijer, Bernard A. Fox, Hong-Ming Hu, Edwin Walker, Sidney Rosenheim, Tarsem Moudgil, Teri Doran, William Wood, Mark Seligman, W. Gregory Alvord, Deric Schoof, Walter J. Urba, Vaccination of Women with Metastatic Breast Cancer, Using a Costimulatory Gene (CD80)-Modified, HLA-A2-Matched, Allogeneic, Breast Cancer Cell Line: Clinical and Immunological Results Human Gene Therapy. ,vol. 14, pp. 1117- 1123 ,(2003) , 10.1089/104303403322124828
Deborah A. Higgins, Julia R. Carlson, Gary Van Nest, MF59 adjuvant enhances the immunogenicity of influenza vaccine in both young and old mice Vaccine. ,vol. 14, pp. 478- 484 ,(1996) , 10.1016/0264-410X(95)00240-2
David M. Lubaroff, Dev Karan, Michael P. Andrews, Anna Acosta, Chadi Abouassaly, Madeva Sharma, Arthur M. Krieg, Decreased cytotoxic T cell activity generated by co-administration of PSA vaccine and CpG ODN is associated with increased tumor protection in a mouse model of prostate cancer Vaccine. ,vol. 24, pp. 6155- 6162 ,(2006) , 10.1016/J.VACCINE.2006.04.022
Morris Pollard, Phyllis H. Luckert, Autochthonous prostate adenocarcinomas in Lobund-Wistar rats: a model system. The Prostate. ,vol. 11, pp. 219- 227 ,(1987) , 10.1002/PROS.2990110303
Jason Hodde, Michael Hiles, Virus safety of a porcine-derived medical device: evaluation of a viral inactivation method. Biotechnology and Bioengineering. ,vol. 79, pp. 211- 216 ,(2002) , 10.1002/BIT.10281
Michal Arbel, Vered Lavie, Beka Solomon, Generation of antibodies against prion protein in wild-type mice via helix 1 peptide immunization. Journal of Neuroimmunology. ,vol. 144, pp. 38- 45 ,(2003) , 10.1016/J.JNEUROIM.2003.08.036
Peter Palese, Making Better Influenza Virus Vaccines Emerging Infectious Diseases. ,vol. 12, pp. 61- 65 ,(2006) , 10.3201/EID1201.051043
David Peretz, R. Anthony Williamson, Kiotoshi Kaneko, Julie Vergara, Estelle Leclerc, Gerold Schmitt-Ulms, Ingrid R. Mehlhorn, Giuseppe Legname, Mark R. Wormald, Pauline M. Rudd, Raymond A. Dwek, Dennis R. Burton, Stanley B. Prusiner, Antibodies inhibit prion propagation and clear cell cultures of prion infectivity Nature. ,vol. 412, pp. 739- 743 ,(2001) , 10.1038/35089090
R Nakaoka, Potentiality of gelatin microsphere as immunological adjuvant Vaccine. ,vol. 13, pp. 653- 661 ,(1995) , 10.1016/0264-410X(94)00024-H
Ellen S. Vitetta, Joan E. Smallshaw, Elaine Coleman, Hasan Jafri, Callie Foster, Robert Munford, John Schindler, A pilot clinical trial of a recombinant ricin vaccine in normal humans. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 2268- 2273 ,(2006) , 10.1073/PNAS.0510893103