作者: She Kaufmann , D Kabelitz
DOI: 10.1016/S0580-9517(08)70675-5
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摘要: Publisher Summary This chapter discusses the mechanism of immune response to infectious agents. It is task system protect host against invading agents, and thereby prevent disease. A plethora microbial pathogens exists that have exploited strategies circumvent an attack by system. Conversely, has evolved provide appropriate defense mechanisms at various levels nonspecific specific responses. The micro-organisms developed different invade their host. Viruses make use cell's machinery for replication are, thus, intracellular pathogens. Intracellular evasion prolong survival inside macrophages. Two well-defined some less subpopulations T cells are involved in cell-mediated expression relevant cell-surface molecules allows identification phenotypic characterization monoclonal antibodies. Th1 Th2 differentiate from undetermined Th0 precursor cell. differentiation into one or other functional subset driven cytokines produced early after infection.