Cytotoxicity of rat macrophages activated by persistent or biodegradable bacterial cell walls.

摘要: Abstract Peritoneal macrophages from Fischer 344 rats were cytotoxic for mouse fibroblasts after in vitro phagocytosis of non-biodegradable group A streptococcal cell walls. In contrast, Buffalo not activated to cytotoxicity by bacterial Activation was only achieved the an interval at least 3 days culture ingestion If cultured 24 h walls, a cytostatic effect on target cells observed. Phagocytosis biodegradable D walls did activate either rat strain become cytotoxic. No direct toxicity or L-cells The appears require contact with cells.