Poorer frontolimbic white matter integrity is associated with chronic cannabis use, FAAH genotype, and increased depressive and apathy symptoms in adolescents and young adults

作者: Skyler G. Shollenbarger , Jenessa Price , Jon Wieser , Krista Lisdahl

DOI: 10.1016/J.NICL.2015.03.024

关键词:

摘要: Background The heaviest period of cannabis use coincides with ongoing white matter (WM) maturation. Further, cannabis-related changes may be moderated by FAAH genotype (rs324420). We examined the association between and on frontolimbic WM integrity in adolescents emerging adults. then tested whether observed abnormalities were linked depressive or apathy symptoms.

参考文章(100)
W-SV Ho, CJ Hillard, None, Modulators of Endocannabinoid Enzymic Hydrolysis and Membrane Transport Handbook of Experimental Pharmacology. ,vol. 168, pp. 187- 207 ,(2005) , 10.1007/3-540-26573-2_6
Géraldine Dorard, Sylvie Berthoz, Olivier Phan, Maurice Corcos, Catherine Bungener, Affect dysregulation in cannabis abusers: a study in adolescents and young adults. European Child & Adolescent Psychiatry. ,vol. 17, pp. 274- 282 ,(2008) , 10.1007/S00787-007-0663-7
P Brimblecombe, Monitoring the future Edipuglia. ,(2010)
Duncan B. Clark, Tammy Chung, Dawn L. Thatcher, Stefan Pajtek, Elizabeth C. Long, Psychological dysregulation, white matter disorganization and substance use disorders in adolescence. Addiction. ,vol. 107, pp. 206- 214 ,(2012) , 10.1111/J.1360-0443.2011.03566.X
MOHAMMAD R. HAYATBAKHSH, JAKE M. NAJMAN, KONRAD JAMROZIK, ABDULLAH A. MAMUN, ROSA ALATI, WILLIAM BOR, Cannabis and Anxiety and Depression in Young Adults: A Large Prospective Study Journal of the American Academy of Child and Adolescent Psychiatry. ,vol. 46, pp. 408- 417 ,(2007) , 10.1097/CHI.0B013E31802DC54D
Viola Oertel-Knöchel, Britta Reinke, Gilberto Alves, Alina Jurcoane, Sofia Wenzler, David Prvulovic, David Linden, Christian Knöchel, Frontal white matter alterations are associated with executive cognitive function in euthymic bipolar patients Journal of Affective Disorders. ,vol. 155, pp. 223- 233 ,(2014) , 10.1016/J.JAD.2013.11.004
Lynn K. Paul, Aaron Lautzenhiser, Warren S. Brown, Arch Hart, Dirk Neumann, Michael Spezio, Ralph Adolphs, Emotional arousal in agenesis of the corpus callosum International Journal of Psychophysiology. ,vol. 61, pp. 47- 56 ,(2006) , 10.1016/J.IJPSYCHO.2005.10.017
A. Giorgio, K.E. Watkins, G. Douaud, A.C. James, S. James, N. De Stefano, P.M. Matthews, S.M. Smith, H. Johansen-Berg, Changes in white matter microstructure during adolescence. NeuroImage. ,vol. 39, pp. 52- 61 ,(2008) , 10.1016/J.NEUROIMAGE.2007.07.043
Fei Wang, Jessica H. Kalmar, Erin Edmiston, Lara G. Chepenik, Zubin Bhagwagar, Linda Spencer, Brian Pittman, Marcel Jackowski, Xenophon Papademetris, R. Todd Constable, Hilary P. Blumberg, Abnormal Corpus Callosum Integrity in Bipolar Disorder: A Diffusion Tensor Imaging Study Biological Psychiatry. ,vol. 64, pp. 730- 733 ,(2008) , 10.1016/J.BIOPSYCH.2008.06.001